Senior Scientist, Translational Research

COMPANY INTRODUCTION   Triveni Bio is breaking new ground in the identification of novel disease targets – working at the convergence of human genetics, best-in-class antibody design, and precision medicine.  We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch – providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect. SUMMARY  Triveni Bio is seeking a highly motivated and experienced Scientist to join our Biology and Translational Research team. In this role, you will lead image-based biomarker analyses and drive the experimental design and execution of cell-based and ex vivo preclinical models. This is an exciting opportunity to shape the scientific biomarker strategy across multiple indications, advancing therapeutics that target novel disease pathways. If you are passionate about therapeutic discovery and possess extensive expertise in image analysis, we want to hear from you. RESPONSIBILITIES

Analyze DIA/DDA proteomics and peptidomics datasets using Spectronaut and Skyline

Lead image-based biomarker analyses using HALO to support biomarker analyses

Design and execute experimental cell-based and ex vivo preclinical models

Oversee external research activities, to meet timelines, deliverables, and data quality with Contract Research Organizations (CROs) or academic collaborators

EXPERIENCE & QUALIFICATIONS

Ph.D. in molecular biology or related a related discipline with 5+ years of experience within the pharmaceutical or biotechnology sectors.

Good understanding of LC-MS/MS principles. Ideally, hands-on experience with running LC-MS/MS workflows and data analysis using Spectronaut and/or Skyline.

Extensive, hands-on expertise in image analysis utilizing HALO.

Solid background in Immunology and Inflammation indications, with a strong preference for specific experience in atopic dermatitis.

Familiarity or expertise in mechanistic cell-based and cell-free assays to investigate type 2 immunity, including immune cells, mast cells, IgE biology, cytokine modulation, and other relevant pharmacodynamic readouts.

Proven track record of effectively managing Contract Research Organizations (CROs), external vendors, and academic collaborators.

The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package.   We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.   Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio or @hire.lever.co. Please disregard any other communications that do not originate from these domain names. If you receive any suspicious requests or communications, please verify their authenticity before responding.