Vice President / Senior Vice President, Clinical Development (AID)

The Vice President/Senior Vice President, Clinical Development will serve as the strategic clinical leader for Janux’s expanding autoimmune pipeline, driving the vision and execution of clinical development programs in autoimmune diseases. This leader, reporting to the CEO, will shape the company’s entry into autoimmune diseases, leveraging a differentiated platform to address significant unmet needs. The VP/SVP will be responsible for high-level strategy, portfolio leadership, and thought partnership with internal and external stakeholders, while ensuring clinical integrity through oversight of medical monitoring. ESSENTIAL FUNCTIONS AND RESPONSIBILITIES:

Set and execute the strategic vision for clinical development in autoimmune diseases, ensuring alignment with corporate goals and maximizing portfolio value.

Lead cross-functional teams in the design and implementation of clinical development strategies, focusing on innovation, differentiation, and speed to market.

Oversee clinical program execution at a strategic level, delegating operational and hands-on responsibilities to clinical teams and direct reports.

Maintain ultimate accountability for medical monitoring, ensuring patient safety and clinical integrity, but delegate day-to-day monitoring activities to appropriate team members.

Provide expert guidance and strategic input on clinical trial design, regulatory strategy, and data interpretation.

Serve as the primary medical and scientific spokesperson for the immunology franchise, internally and externally.

Cultivate relationships with key opinion leaders, investigators, and external partners to advance Janux’s immunology pipeline.

Drive organizational growth, talent development, and succession planning within the clinical development function.

Other duties as deemed essential

EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES

MD or DO with subspecialty in immunology, autoimmune diseases, or related fields.

Demonstrated success as a senior clinical leader (e.g., therapeutic area head, franchise lead) in large pharma or biotech, with broad immunology experience.

Proven track record of strategic leadership in clinical development, portfolio management, and cross-functional team building.

Innovative, entrepreneurial mindset; experience driving change and building new capabilities.

Deep understanding of early drug development, clinical trial processes, and regulatory requirements in immunology/inflammation.

Exceptional communication, influence, and stakeholder management skills.

Strong ability to critically evaluate data, literature, and presentations.

High level of communication skills is expected.

Job Type: Full-time Benefits: ·             Annual bonus program ·             Incentive stock option plan ·             401k plan with flat non-elective employer contribution ·             Comprehensive medical insurance with 90-100% employer-paid premiums ·             Dental and vision insurance ·             HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity) ·             Unlimited PTO ·             Generous holiday schedule; includes summer and winter company shutdown ·             Relocation assistance Schedule: ·             Monday to Friday Work authorization: ·             United States (Required) Additional Compensation: ·             Annual targeted bonus % Work Location: ·             Hybrid preferred in San Diego office. Remote permitted upon approval, with ability to travel up to 25% for meetings or site visits as required.   EQUAL OPPORTUNITY EMPLOYER: Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.